Faculty : Faculty

Feng Gong, PhD

Associate Professor of Biochemistry and Molecular Biology
Associate Director of the BMB Executive PhD Program
FBS1 Course Coordinator
Co-director of Molecular Medicine Pathway
Primary Appointment of Biochemistry and Molecular Biology
(305) 243-9270
fgong@med.miami.edu
Gautier Building Room #303
Research Summary: To understand the mechanisms of chromatin dynamics during DNA repair.
Publications: PubMed

Clinical Interests:

We are interested in the development of DUB inhibitors in cancer therapy.

Research Interests:

My research group is presently investigating the role of the SWI/SNF chromatin remodeling complex in DNA repair and the role of USP24 in tumor suppression. We recently show that USP24 regulates the stability of p53 and is a potential tumor suppressor. Evidence also indicates that SWI/SNF has a widespread role in tumor suppression, as inactivating mutations in several SWI/SNF subunits have recently been identified at a high frequency in a variety of cancers, including breast cancer.

Besides research, I am actively involved in teaching undergraduate students and MD and PhD graduate students. I am the course director for the MD “Fundamentals of Biomedical Sciences 1 (FBS1)”. I am also the course director of BMB519 “Epigenetics and Nutrition”. In addition, my laboratory provides an appropriate environment to train graduate students on analysis of DNA repair associated chromatin dynamics and the novel roles of DUBs in DNA repair. My expertise in DNA damage repair and chromatin biology and history of mentorship of graduate and post-graduate trainees will serve to help provide an environment for trainees to acquire research skills and the intellectual rigor to sustain independent careers in basic and translational cancer research.

Awards:

Young Investigator Award from the Concern Foundation for Cancer Research

Education:

1998 PhD The Chinese Academy of Sciences, Shanghai Institutes of Biological Sciences